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The Interaction of Steroid Nasal Sprays with Some Drugs


People who are already taking steroid nasal sprays should always consult their doctor before taking any additional prescriptions, over-the-counter medications, herbal or nutritional supplements. Some medications may interfere with the body's ability to expel steroids. These medications are the following:

Ephedrine. This powerful bronchodilator rapidly opens the airways. It can however, decrease the blood levels of some nasal corticosteroids. Individuals taking ephedrine need a higher dosage of steroid nasal sprays.

Ketoconazole.  This is an anti-fungal medication primarily used for infections of the mouth (thrush), nails, lungs, vagina, and blood. Ketoconazole is believed to hamper the elimination of budesonide from the body.

Phenobarbital.   A barbiturate, or sedative, this drug is used to treat epilepsy, insomnia, and anxiety. It can however, decrease the blood levels of some nasal corticosteroids.  Patients taking this drug need a higher dosage of steroid nasal sprays.

Rifampin. An antibacterial medication primarily used to treat tuberculosis, this drug can decrease the blood levels of some nasal corticosteroids. Individuals taking this drug also need a high level of steroid nasal sprays.

Just to on the safe side, make it a point to consult your doctor before taking steroid nasal sprays. You will never know what the best dosage is for you. Let it be handled by professionals.

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